Diagnosis and Treatment of Venous Thromboembolism
Keywords:
Venous thromboembolism, Modeling, Thrombosis, Hemo-dynamics, Deep vein thrombosis, Pulmonary embolism, Body mass index, DiagnosisAbstract
Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, is a condition characterized by abnormal blood clot formation in the pulmonary arteries and the deep venous vasculature. It is often serious and sometimes even fatal if not promptly and appropriately treated. Moreover, the later consequences of VTE may result in reduced quality of life. The treatment of VTE depends on various factors, including the type, cause, and patient comorbidities. Furthermore, bleeding may occur as a side effect of VTE treatment.In populations, but recent studies have shown an increase in the incidence of VTE in Asia. A variety of treatment options are currently available owing to the introduction of direct oral anticoagulants. The current VTE treatment recommendation is based on evidence from previous studies, but it should be applied with careful consideration of the racial, genetic, and social characteristics in the Korean population.
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References
Raju S, Fredericks RK. Late hemodynamic sequelae of deep venous thrombosis. Journal of vascular surgery. 1986 Jul 1;4(1):73-9.
https://doi.org/10.1016/0741-5214(86)90325-3 .
Kroegel C, Reissig A. Principle mechanisms underlying venous thromboembolism: epidemiology, risk factors, pathophysiology and pathogenesis. Respiration. 2003 Feb 17;70(1):7-30.
https://doi.org/10.1159/000068427 .
Prins MH, Bamber L, Cano SJ, Wang MY, Erkens P, Bauersachs R, Lensing AW. Patient-reported treatment satisfaction with oral rivaroxaban versus standard therapy in the treatment of pulmonary embolism; results from the EINSTEIN PE trial. Thrombosis research. 2015 Feb 1;135(2):281-8.
https://doi.org/10.1016/j.thromres.2014.11.008 .
Henke PK, Kahn SR, Pannucci CJ, Secemksy EA, Evans NS, Khorana AA, Creager MA, Pradhan AD, American Heart Association Advocacy Coordinating Committee. Call to action to prevent venous thromboembolism in hospitalized patients: a policy statement from the American Heart Association. Circulation. 2020 Jun 16;141(24):e914-31.
https://doi.org/10.1161/CIR.0000000000000769 .
Albertsen IE, Nielsen PB, Søgaard M, Goldhaber SZ, Overvad TF, Rasmussen LH, Larsen TB. Risk of recurrent venous thromboembolism: a Danish nationwide cohort study. The American Journal of Medicine. 2018 Sep 1;131(9):1067-74.
https://doi.org/10.1016/j.amjmed.2018.04.042 .
Gupta N, Zhao YY, Evans CE. The stimulation of thrombosis by hypoxia. Thrombosis research. 2019 Sep 1;181:77-83.
https://doi.org/10.1016/j.thromres.2019.07.013 .
White RH. The epidemiology of venous thromboembolism. Circulation. 2003 Jun 17;107(23_suppl_1):I-4.
https://doi.org/10.1161/01.CIR.0000078468.11849.66 .
Hwisa NT, Gindi S, Rao CB, Katakam P, Rao Chandu B. Evaluation of Antiulcer Activity of Picrasma Quassioides Bennett Aqueous Extract in Rodents. Vedic Res. Int. Phytomedicine. 2013;1:27.
https://doi.org/10.1177/02683555241259616 .
Dara SR. An Overview of the Use of Natural Indicators in Acid-Base Titrations. UPI Journal of Pharmaceutical, Medical and Health Sciences. 2024 Jul 23:29-35.
https://doi.org/10.1161/01.CIR.0000078469.07362.E6 .
Nama S, Chandu BR, Awen BZ, Khagga M. Development and validation of a new RP-HPLC method for the determination of aprepitant in solid dosage forms. Tropical Journal of Pharmaceutical Research. 2011;10(4):491-7.
https://doi.org/10.1016/j.chest.2015.11.026
Horner D, Hogg K, Body R, Nash MJ, Baglin T, Mackway-Jones K. The anticoagulation of calf thrombosis (ACT) project: results from the randomized controlled external pilot trial. Chest. 2014 Dec 1;146(6):1468-77.
https://doi.org/10.1378/chest.14-0235 .
Riera-Mestre A, Becattini C, Giustozzi M, Agnelli G. Thrombolysis in hemodynamically stable patients with acute pulmonary embolism: a meta-analysis. Thrombosis research. 2014 Dec 1;134(6):1265-71.
https://doi.org/10.1016/j.thromres.2014.10.004 .
Buller HR. Oral rivaroxaban for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN DVT and EINSTEIN PE studies. Blood. 2012 Nov 16;120(21):20.
https://doi.org/10.1182/blood.V120.21.20.20 .
Raskob GE. Importance of subsegmental pulmonary embolism. Blood, The Journal of the American Society of Hematology. 2013 Aug 15;122(7):1094-5.
https://doi.org/10.1182/blood-2013-06-508440 .
Martínez-Zapata MJ, Mathioudakis AG, Mousa SA, Bauersachs R. Tinzaparin for long-term treatment of venous thromboembolism in patients with cancer: a systematic review and meta-analysis. Clinical and Applied Thrombosis/Hemostasis. 2018 Mar;24(2):226-34.
https://doi.org/10.1177/1076029617696581
Hwisa NT, Gindi S, Rao CB, Katakam P, Rao Chandu B. Evaluation of Antiulcer Activity of Picrasma Quassioides Bennett Aqueous Extract in Rodents. Vedic Res. Int. Phytomedicine. 2013;1:27.
https://www.researchgate.net/publication/248995990
Gindi S, Methra T, Chandu BR, Boyina R, Dasari V. Antiurolithiatic and invitro anti-oxidant activity of leaves of Ageratum conyzoides in rat. World J. Pharm. Pharm. Sci. 2013 Feb 8;2:636-49.
https://www.researchgate.net/profile/Revathi-Boyina/publication/251566463
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