Prescribing patterns and analyzing the usage of corticosteroid therapy at tertiary care hospital
DOI:
https://doi.org/10.37022/jpmhs.v7i1.99Keywords:
Corticosteroids, Auto immune diseases, CDSCO, dermatitis, tachyphylaxis, MyelosuppressionAbstract
Corticosteroids are used extensively in treating inflammation. They provide short-term symptomatic relief in abnormalities of conditions like Auto immune diseases, Dermatological and Respiratory diseases. Adverse effects of Corticosteroids include Cushing’s syndrome, Skin atrophy, contact dermatitis, tachyphylaxis, Myelosuppression, Diabetes mellitus, Hypertension, pleural effusion. As per the sources available from the regulatory authority of Central Drugs Standard Control organization, inappropriate use of Corticosteroids is more commonly practiced in India almost all the drugs are prescribed rationally. The Pharmacist can promote better patient care and drug safety. Most of the Physician is recommending the drugs are mostly branded names. Our study suggests provide it in generic names. Clinical Pharmacists in associations with clinicians must play a crucial role in minimizing the problems associated with irrational usage of corticosteriods.
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References
Yik-Hong Ho, Margaret Tan, Chan-Hong Chui, Adrian Leong, Kong-Weng Eu, and Francis Seow-Choen, “Randomized controlled trial of primary fistulotomy with drainage alone for perianal abscesses”, “Diseases of the Colon & Rectum, Volume 40, Issue 12”Klein KB. Controlled treatment trials in irritable bowel syndrome. a critique. Gastroenterology 1988;95:232–41.
Douglas A Drossman and Dan L Dumitrascu, “Rome III: New Standard for Functional Gastrointestinal Disorders”, “J Gastrointestin Liver Dis Vol.15 No.3, 237-241”
DOUGLAS A. DROSSMAN, “The Functional Gastrointestinal Disorders and the Rome III Process”, “GASTROENTEROLOGY; 130:1377–1390”
Osama Alaradi and Jamie S. Barkin, “Irritable Bowel Syndrome: Update on Pathogenesis and Management”, “Medical Principles And Practice”
Pal D, Sahoo M, Mishra AK. Analgesic and anticonvulsant effects of saponin isolated from the stems of Opuntia vulgaris Mill in mice. Eur Bull Drug Res. 2005;13:91-7.
Fermin Mearin and Peter Malfertheiner, “Functional Gastrointestinal Disorders: Complex Treatments for Complex Pathophysiological Mechanisms”, “Digestive Diseases”
Vincenzo Stanghellini, “Functional Dyspepsia and Irritable Bowel Syndrome: Beyond Rome IV”, “Digestive Diseases”
Gerald Holtmann, Ayesha Shah, and Mark Morrison, “Pathophysiology of Functional Gastrointestinal Disorders: A Holistic Overview”, “Digestive Diseases”
Pal DK, Sahoo M, Mishra AK. Anthelmintic activity of stems of Opuntia vulgaris Mill.
S J O Veldhuyzen van Zanten, N J Talley, P Bytzer, KB Klein, P J Whorwell and A R Zinsmeister, “The functional gastrointestinal disorders and the Rome II Process”, “GUT: 45(Suppl II): II69–I77)”
Marie R. Griffin, Joyce M. Piper, James R. Daugherty, Mary Snowden, and Wayne A. Ray, “Nonsteroidal Anti-inflammatory Drug Use and Increased Risk for Peptic Ulcer Disease in Elderly Persons”, “Annals Of Internal Medicine”
Edward L. Bradley III, “A Clinically Based Classification System for Acute Pancreatitis”, “JAMA SURGERY”
Pal D, Raj K, Nandi SS, Sinha S, Mishra A, Mondal A, Lagoa R, Burcher JT, Bishayee A. Potential of synthetic and natural compounds as novel histone deacetylase inhibitors for the treatment of hematological malignancies. Cancers. 2023 May 17;15(10):2808.
Mal S, Malik U, Mahapatra M, Mishra A, Pal D, Paidesetty SK. A review on synthetic strategy, molecular pharmacology of indazole derivatives, and their future perspective. Drug Development Research. 2022 Nov;83(7):1469-504.
Jean PaulGalmiche, Ray E.Clouse, AndrásBálint, Ian J.Cook, Peter J.Kahrilas, William G.Paterson, and Andre J.P.M.Smout, “Functional Esophageal Disorders”, “Gastroenterology Volume 130, Issue 5”
HJ Stein, A P Barlow, T R DeMeester, and R A Hinder, “Complications of gastroesophageal reflux disease. Role of the lower esophageal sphincter, esophageal acid, and acid/alkaline exposure, and duodenal-gastric reflux”, “Annals Of Surgery”
Mal S, Malik U, Pal D, Mishra A. Insight γ-Secretase: Structure, Function, and Role in Alzheimer's Disease. Current drug targets. 2021;22(12):1376-403.
Donald Earl Henson, Jorge Albores-Saavedra and Donald Code, “Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates”, “Cancer”
J Escourrou, J A Cordova, F Lazorthes, J Frexinos, and A Ribet, “Early and late complications after endoscopic sphincterotomy for biliary lithiasis with and without the gall bladder-in situ”, “GUT Volume 25, Issue 6”
Pal D, Raj K, Nandi SS, Sinha S, Mishra A, Mondal A, Lagoa R, Burcher JT, Bishayee A. Potential of synthetic and natural compounds as novel histone deacetylase inhibitors for the treatment of hematological malignancies. Cancers. 2023 May 17;15(10):2808.
A.R.W.Hatfield, J.Terblanche, S.Fataar, L.Kernoff, R.Tobias, A.H.Girdwood, R.Harries-Jones, and I.N.Marks, “PREOPERATIVE EXTERNAL BILIARY DRAINAGE IN OBSTRUCTIVE JAUNDICE: A Prospective Controlled Clinical Trial”, “NEJM Volume 320, Issue 8304”
AntonyG.Speer, R.Christopher, G.Russell, AdrianR.W.Hatfield, Kenneth D.Macrae, PeterB.Cotton, Richard R.Mason, JosephW.C.Leung, Joan Houghton, and Christin aA.Lennon, “RANDOMISED TRIAL OF ENDOSCOPIC VERSUS PERCUTANEOUS STENT INSERTION IN MALIGNANT OBSTRUCTIVE JAUNDICE”, “NEJM”
Feran Agachan, Teng Chen, Johann Pfeifer, Petachia Reissman and Steven D. Wexner, “A constipation scoring system to simplify evaluation and management of constipated patients”, “Diseases of the Colon & Rectum, Volume 39, Issue 6”
Anthony Lembo and Michael Camilleri, “Chronic Constipation”, “THE NEW ENGLAND JOURNAL OF MEDICINE”
Denise J.Jamieson and John F.Steege, “The prevalence of dysmenorrhea, dyspareunia, pelvic pain, and irritable bowel syndrome in primary Care Practices”, “Obstetrics & Gynecology, Volume 87, Issue 1”
LiamO’Mahony, Jane McCarthy, PeterKelly, GeorgeHurley‡FangyiLuo, KersangChen, Gerald C.O Sullivan, BarryKiely, J. KevinCollins, Fergus Shanahan, and Eamonn M.M.Quigley, “Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles”
Douglas K.Rex, DavidVining, and Kenyon K.Kopecky, “An initial experience with screening for colon polyps using spiral CT with and without CT colonography (virtual colonoscopy)”, “Gastrointestinal Endoscopy Volume 50, Issue 3,”
Mark H. Whiteford, John Kilkenny III, Neil Hyman, W. Donald Buie, Jeffrey Cohen, Charles Orsay, Gary Dunn, W. Brian Perry, C. Neal Ellis, Jan Rakinic, Sharon Gregorcyk, Paul Shellito, Richard Nelson, Joe J. Tjandra and Graham Newstead, “Practice Parameters for the Treatment of Perianal Abscess and Fistula-in-Ano (Revised)”, “Diseases of the Colon & Rectum, Volume 48, Issue 7,”
Frank Makowiec, Ekkehard C. Jehle, Horst-Dieter Becker, and Michael Starlinger, “Perianal abscess in Crohn's disease”, “Diseases of the Colon & Rectum, Volume 40, Issue 4”
S J O Veldhuyzen van Zanten, N J Talley, P Bytzer, KB Klein, P J Whorwell and A R Zinsmeister, “Design of treatment trials for functional gastrointestinal disorders”, “GUT: 45(Suppl II): II69–II77)”
Veldhuyzen van Zanten SJO, Cleary C, Talley NJ, et al. Drug treatment of functional dyspepsia. A systematic analysis of trial methodology with recommendations for the design of future trials. Am J Gastroenterol 1996;91:660–71.
Talley NJ, Nyren O, Drossman DA, et al.The irritable bowel syndrome.Toward optimal design of controlled treatment trials. Gastroenterol Int 1993;6:189–211.
Drossman DA, Richter JE, Talley NJ, et al (eds). The functional gastrointestinal disorders: diagnosis, pathophysiology, and treatment. McLean, VA: Degnon Associates, 1994.
Drossman DA, Thompson WG, Talley NJ, et al. Identification of subgroups of functional gastrointestinal disorders. Gastroenterol Int 1990;3:159–72.
Talley NJ, Weaver AL, Tesmer DL, et al. Lack of discriminant value of dyspepsia subgroups in patients referred for upper endoscopy. Gastroenterology 1993;105:1378–86.
Klauser A, Voderholzer WA, Knesewitsch PA, et al. What is behind dyspepsia? Dig Dis Sci 1993;38:147–54.
Talley NJ,Meineche-Schmidt V, Pare P, et al. Omeprazole is efficacious in non-ulcer dyspepsia. Can J Gastroenterol 1998;12(suppl):70–71A.
Lavori PW, Louis TA, Bailar JC III, et al. Designs for experiments. Parallel comparisons of treatment. N Engl J Med 1983;309:1291–8.
Pal D, Pahari SK, Mishra AK. Anthelmintic activities of roots of Cocos nucifera and aerial parts of Jasminum multiflorum. Asian journal of chemistry. 2007 Oct 1;19(7):5089.
O’Donoghue DP, Dawson AM, Powell-Tuck Brown RL, et al. Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn’s disease. Lancet 1978;ii:955–7.
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