Evaluation of invitro antiurolithiatic activity of ethanolic and methanolic leaf extracts of acalypha indica linn.

Ravi Kumar Konda; Prathyusha A

doi:10.37022/jpmhs.v3i1.15

Authors

Konda Ravi Kumar Professor, Department of Pharmaceutical Chemistry, Hindu College of Pharmacy, Amaravathi Road, Guntur-522002. A.P, India.
A.Prathyusha Assistant Professor, Department of Pharmacology, Hindu College of Pharmacy, Amaravathi Road, Guntur-522002. A.P, India.

DOI:

https://doi.org/10.37022/jpmhs.v3i1.15

Keywords:

Acalypha indica Linn, Urolithiasis, In-vitro Evaluation, Methanolic and Ethanolic Extracts

Abstract

The claims of Acalypha indica.L antiurolithiatic effect have not been established experimentally. The present study is designing to evaluate the invitro anti-urolithiatic activity of Ethanolic and methanolic leaf extracts of Acalypha indica.L. Urolithiasis is a common and a major cause of morbidity worldwide. Acalypha is widely utilized in traditional medicine systems. Traditional communities in India use this plant as an analgesic, anti-inflammatory, anti-helminthic, anti-bacterial, anti-fungal, anti-tubercular, antioxidant, molluscicidal, anti-venom, anti-ulcer, etc. So far, the claims of Acalypha indica antiurolithiatic activity have not been confirmed experimentally. The present study is designed to evaluate the invitro anti-urolithiatic activity of Ethanolic and methanolic leaf extracts of Acalypha indica Linn.

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References

Kala, Chandra Prakash; Sajwan (2007). "Revitalizing Indian systems of herbal medicine by the National Medicinal Plants Board through institutional networking and capacity building". Current Science. 93 (6): 797–806.

Saad, Bashar & Said, Omar (2011). Greco-Arab and Islamic Herbal Medicine: Traditional System, Ethics, Safety, Efficacy, and Regulatory Issues. John Wiley & Sons. p. 80. ISBN 9780470474211.

Acalypha indica L. Indian Acalypha, on India Biodiversity Portal (http://indiabiodiversity. Org/species/show/32852). Accessed 31.07.2017.

Hong, Francis (2004). "History of Medicine in China" (PDF). McGill Journal of Medicine. 8 (1): 7984. Archived from the original (PDF) on 2013-12-01.

Scaffidi, Adrian; Algar, Dave; Bohman, Björn; Ghisalberti, Emilio L; Flematti, Gavin (2016). “Identification of the Cat Attractants Isodihydronepetalactone and Isoiridomyrmecin from Acalypha indica”. Australian Journal of Chemistry. 69(2): 169. doi: 10.1071/CH15476 (https://doi.org/10.1071%2FCH15476).

M Aminuar Rahman, Sitesh C Bachar and Mohammed Rahmatullah, Analgesic and Antiinflammoraty activity of methanolic extract of Acalypha indica L., Pak. J. Pharm. Sci., Vol.23, No.3, July 2010, pp.256-258

B. Chengaiah, K. Mahesh Kumar, M. Alagusundaram, C. Sasikala, C. Madhusudhan Chetty, In- vitro Antihelmintic activity of root of Acalypha Indica Linn. International Journal of PharmTech Research, Vol.1, No.4, pp 1499-1502, Oct-Dec 2009.

Lakshmi, S, Antibacterial potential of Acalypha Indica against human pathogens, International Journal of Current Research, Vol. 1, pp. 001-004, January, 2010.

Omar, R., Ali Rahman, Z., Latif, M.T., Lihan, T. and Adam J.H, In Vitro Antibacterial and antifungal properties of Acalypha indica (KUCING GALAK) Proceedings of the Regional Symposium on Environment and Natural Resources 10-11th April 2002 Vol 1: 503-508.

Renu Gupta, Bandana Thakur, Pushpendra Singh, H.B. Singh, V.D. Sharma, V.M. Katoch & S.V.S. Chauhan, Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates, Indian J Med Res 131, June 2010, pp 809-813.

Beena Joy, Molly Mathew, Anti-oxidant studies and chemical investigation of ethanol extract of Acalypha indica Linn. Recent Progress in Medicinal Plants, Volume 27

S. Sharma, T. Singh and R. Vijayvergia, Molluscicidal activity of some medicinal plants, Journal of Herbal Medicine and Toxicology 3 (2) 155-157 (2009).

Ernie H. Purwaningsih, Nurhadi Ibrahim, Hamdani Zain , Arjo Tedjo, Neuro-protection and neuro-therapy effects of Acalypha indica Linn. Water extract ex vivo on musclus gastrocnemius Frog, MAKARA, KESEHATAN, VOL. 12, NO. 2, December 2008: 70-75

K. Rajendran1, Annie Shirwaikar, Maneesh Mehta, R. Vijaya Bharathi, In vitro and in vivo anti-snake venom (Daboia russelli) studies on various leaf extracts of Acalypha indica Linn, International Journal of Phytomedicine 2 (2010) 217-220

S. Kalimuthu, P. Rajesh, V. Rajesh Kannan, B. Balamurugan, T.M. Chandrasekar, Antiulcer activity of Methanolic extract of Acalypha indica Linn. (Euphorbiaceae) by Pylorous Ligture and Swim Stress Induced Ulceration, Journal of Pharmacy Research 2010, 3(11), 2779-2783.

Byahatti,Pai Vasanth Kumar. Effect of phenolic compounds from Bergenia cliata ( Haw). Sternb.leaves on experimental kidney stones. Ancient Science of Life 2010;30(1):14-17.