A Review of Recent Techniques for Granulation

Sravani  Thalari

doi:10.37022/jpmhs.v7i3.113

Authors

Thalari Sravani Priyadarshini Institute of Pharmaceutical Education and Research, 5th Mile, Pulladigunta, Guntur-522017.Andhra Pradesh, India.

DOI:

https://doi.org/10.37022/jpmhs.v7i3.113

Keywords:

Granulation, foam granulation, stream granulation, thermal adhesion granulation

Abstract

Granulation is the process of designing particles by combining primary power particles into massive multiparticle structures known as granules. Its primary purposes are to boost the flow of power, prevent segregation, improve the compaction characteristics of mix uniformity, and improve the flow and compressibility of powders. It also produces a combination that is uniform. Wet granulation and dry granulation are the two primary categories of granulation methods. The granulation process is contingent upon the description of the ingredient entity and its ability to surge appropriately, compact, and collapse. Choosing the appropriate granulation method necessitates a methodical examination of each ingredient in the combination and how they interact. Granule particle size is determined by the amount and feeding rate of the granulating liquid. New methods have been added to the granulation process to improve it: foam binder granulation, fluidized bed granulation, melt granulation, activated dry granulation, heat adhesion granulation, steam granulation, spray drying granulation, and freeze granulation. The major purpose of this page is to provide an overview of each advancement, including its limitations and relevance.

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